How To Calculate Human Equivalent Dose

Human Equivalent Dose (HED) calculation is crucial in toxicology and pharmacology to compare doses between species. It ensures the safety and efficacy of drugs and chemicals.

How to Use This Calculator

1. Select the dose from the dropdown menu.
2. Enter the weight in kilograms.
3. Click ‘Calculate’.

Formula & Methodology

The formula used is: HED = Animal Dose (mg/kg) * (Animal Weight (kg) / Human Weight (kg)) * Assumption Factor.

Real-World Examples

Data & Statistics

Comparison of Doses

Species	Weight (kg)	Dose (mg/kg)	HED (mg)

Expert Tips

• Always use the most recent body weight data.
• Consider using allometric scaling for more accurate results.

Interactive FAQ

What is the Assumption Factor?

The Assumption Factor is a safety factor used to account for inter-species variability.

For more information, see the FDA’s guidance on HED calculation and the NTP’s report on HED methodology.